INCIC

CMR highlights

The most relevant papers from cardiac imaging journals, selected and reviewed by INCIC.

Week of Oct 5, 2026

J Cardiovasc Magn ResonPMID 42805342

CMR Reference Values

Left ventricular diastolic function and atrial sphericity parameters were studied in 503 healthy Chinese adults. Men showed significantly different values in parameters such as LACI (0.19 vs 0.20) and LASI (0.52 vs 0.59) compared to women. These findings are important for standardized interpretation of cardiac magnetic resonance parameters in clinical practice

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J Cardiovasc Magn ResonPMID 42805344

Cardiac Diffusion Tensor Imaging

The cardiac diffusion tensor imaging (cDTI) technique with up to 6th order motion compensation was studied. The results show that 4th order compensation is necessary for successful diastolic acquisitions, with mean diffusivity values of (1.73 ± 0.19) × 10-3mm2∕s. This enables reliable quantification of myocardial microstructural changes between systole and diastole, a step towards clinical translation of dynamic cDTI.

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Circ Cardiovasc ImagingPMID 42808160

Cardiac Imaging in Valve Trials

The role of multimodal imaging in transcatheter mitral valve interventions for secondary mitral regurgitation was studied. Imaging criteria for patient selection and key findings after device implantation were examined. This is important for patient selection and follow-up in clinical practice

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JACC Cardiovasc ImagingPMID 42808932

Quantitative Myocardial Perfusion Assessment

PET/CT and CMR techniques were compared for myocardial perfusion evaluation. Both modalities offer high accuracy for detecting flow-limiting coronary stenoses. This is important in clinical practice for improving diagnosis and management of coronary artery disease

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Eur Heart JPMID 42830666

Semaglutide in heart failure

The effect of semaglutide was studied in preclinical models of heart failure with preserved ejection fraction. It was found that semaglutide improves diastolic function and reduces cardiac hypertrophy by 30% and left ventricular filling pressure by 60% without significant weight loss. This is important because it suggests that semaglutide may be beneficial in clinical practice for treating this condition

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Week of Sep 28, 2026

JACC Cardiovasc ImagingPMID 42762217

CMR T1/T2 mapping reflects mechanistic severity in HFpEF beyond filling pressure

In 52 invasively confirmed HFpEF patients (multicentre DECIPHER study), corrected native T1 was associated with passive stiffness (β) and T2 with active relaxation (τ), independent of end-diastolic pressure. Mapping separated mild and severe diastolic dysfunction phenotypes that filling pressure did not; the authors consider this hypothesis-generating.

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J Cardiovasc Magn ResonPMID 42790709

Non-contrast CMR reveals impaired oxygen extraction and energy efficiency in dilated cardiomyopathy

In 49 patients with dilated cardiomyopathy and 23 controls, a non-contrast CMR technique showed lower myocardial oxygen extraction fraction (50.3% vs 57.6%) and lower mechano-energetic efficiency (22.9% vs 46.0%), with higher total oxygen consumption. Efficiency correlated with LVEF and global longitudinal strain. Feasibility study.

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JACC Cardiovasc ImagingPMID 42799727

Contrast-free native T1 for diagnosis and risk in transthyretin cardiac amyloidosis

In 1,675 subjects from a national referral centre, native T1 ≤1,050 ms made cardiac involvement unlikely (93% sensitivity, 84% specificity) and ≥1,100 ms identified overt ATTR-CM (75% and 88%). ECV-calibrated T1 strata reproduced a 3-year mortality gradient; ECV remains preferred when contrast is available, and thresholds need local recalibration.

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J Cardiovasc Magn ResonPMID 42800640

Ventricular quantification in arrhythmias

The feasibility of real-time cardiac magnetic resonance (CMR) for ventricular quantification in arrhythmic patients was studied. The results showed that the technique can reveal functional heterogeneity in patients with premature ventricular contractions (PVC), with broader and sometimes bimodal ejection fraction (EF) distributions. This may be important in clinical practice to improve the evaluation of cardiac function in arrhythmic patients.

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