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The most relevant papers from cardiac imaging journals, selected and reviewed by INCIC.

JACC Cardiovasc Imaging

CMR T1/T2 mapping reflects mechanistic severity in HFpEF beyond filling pressure

In 52 invasively confirmed HFpEF patients (multicentre DECIPHER study), corrected native T1 was associated with passive stiffness (β) and T2 with active relaxation (τ), independent of end-diastolic pressure. Mapping separated mild and severe diastolic dysfunction phenotypes that filling pressure did not; the authors consider this hypothesis-generating.

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J Cardiovasc Magn Reson

Non-contrast CMR reveals impaired oxygen extraction and energy efficiency in dilated cardiomyopathy

In 49 patients with dilated cardiomyopathy and 23 controls, a non-contrast CMR technique showed lower myocardial oxygen extraction fraction (50.3% vs 57.6%) and lower mechano-energetic efficiency (22.9% vs 46.0%), with higher total oxygen consumption. Efficiency correlated with LVEF and global longitudinal strain. Feasibility study.

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JACC Cardiovasc Imaging

Contrast-free native T1 for diagnosis and risk in transthyretin cardiac amyloidosis

In 1,675 subjects from a national referral centre, native T1 ≤1,050 ms made cardiac involvement unlikely (93% sensitivity, 84% specificity) and ≥1,100 ms identified overt ATTR-CM (75% and 88%). ECV-calibrated T1 strata reproduced a 3-year mortality gradient; ECV remains preferred when contrast is available, and thresholds need local recalibration.

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